Leukocyte adhesion defect type 1 presenting with recurrent pyoderma gangrenosum
نویسندگان
چکیده
منابع مشابه
Leukocyte Adhesion Deficiency Type 1 Presenting as Leukemoid Reaction
The hallmarks of leukocyte adhesion deficiency (LAD) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. These molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. Over las...
متن کاملleukocyte adhesion deficiency type 1 presenting as leukemoid reaction
the hallmarks of leukocyte adhesion deficiency (lad) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. these molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. over las...
متن کاملPyoderma gangrenosum presenting with acute generalised haemorrhagic bullae
Tuen Mun Social Hygiene Clinic, 9/F, Ambulatory Care Centre, Tuen Mun Hospital, Tuen Mun, N.T., Hong Kong A 31-year-old Chinese man presented with acute generalised bullous eruption followed by painful ulcers formation with bluish edge. The skin biopsy was consistent with the clinical diagnosis of pyoderma gangrenosum. Subsequent workup did not identify any underlying or associated medical diso...
متن کاملLeukocyte adhesion deficiency type 1 presenting as leukemoid reaction.
Leukocyte Adhesion Deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the blood stream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become necrotic because of abnormal wound healing. LAD-I is characterized by the absence of the beta-2 integrins CD II and CD 18 on leukocytes. We present ...
متن کاملLeukocyte Adhesion Deficiency Type 1 Presenting as Leukemoid Reaction
The hallmarks of leukocyte adhesion deficiency (LAD) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. These molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. Over las...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2013
ISSN: 0019-5154
DOI: 10.4103/0019-5154.108076